• Question: Have you found an antibiotic able to break the recistance yet and if so what isit called?

    Asked by keelerjack010 to Jim on 21 Jun 2011.
    • Photo: Jim Caryl

      Jim Caryl answered on 21 Jun 2011:


      There are a variety of antibiotics that can be used to treat even the most resistant type of bacteria I work on, and they include vancomycin, daptomycin and linezolid. However, no one of such drugs would work in ALL cases of resistant Staph, which is why we routinely determine the susceptibility of all infection bacteria, to see what will work. Sometimes we are able to combine multiple antibiotics to have a greater effect, or combine an antibiotic together with another chemical (an inhibitor) that stops the ability of that bacteria to resist the antibiotic. So an infection that doesn’t respond to treatment with a penicillin medicine called amoxicillin because the bacteria is able to chew up the amoxicillin before it causes damage, might respond to the medicine Augmentin, which is a combination of amoxicillin and another agent called clavulonic acid; the clavulonic acid inhibits the enzymes the bacteria uses to break down the amoxicillin.

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