• Question: if a person had an accident and cant move his legs, do you think it is possible to make it move again?

    Asked by edenbd97 to Richard on 15 Jun 2011.
    • Photo: Richard Badge

      Richard Badge answered on 15 Jun 2011:


      Hi edenbd57

      The amazing thing is that these types of injuries are being treated better and better, with more chance that people will recover. Although I am not a doctor I have read that a lot of the problem with healing damaged nerves is the inflammation that occurs just after injury – if we can control that, then nerve regrowth might be successful.

      Having said that research on stems cells – special cells in the body that can be “persuaded” to turn into any tissue (including nerves) offer huge potential to rebuild damaged body parts and even organs. It might be possible in the future to take some of your own stem cells and grow replacement nerves or heart cells in the lab for trasplantation later.

      Finally regenerating lost structures as complicated as limbs is not that uncommon in nature – amphibians like salamanders are really good at it. This suggests that the ability to do this used to exist in vertebrates (animals with backbones) but was lost for some reason…

      Interestingly there are breeds of mice that can completely regenerate small wounds – this was discovered by accident in a lab where different shaped holes punched in the mouse ear were used to identify the mice. Unfortunately on group of mice healed up their holes and so got all mixed up… This shows that in some circumstances amazing healing is possible…

      More details on these mice here: http://www.ncbi.nlm.nih.gov/pubmed/9683548?dopt=Abstract&holding=npg

      Richard

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